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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGAP2
All Species:
17.58
Human Site:
S439
Identified Species:
38.67
UniProt:
Q99490
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99490
NP_001116244.1
1192
124674
S439
Q
V
L
E
K
T
E
S
E
Q
Y
K
K
E
M
Chimpanzee
Pan troglodytes
XP_509171
1192
124575
S439
Q
V
L
E
K
T
E
S
E
Q
Y
K
K
E
M
Rhesus Macaque
Macaca mulatta
XP_001116285
1192
124611
S439
Q
V
L
E
K
T
E
S
E
Q
Y
K
K
E
M
Dog
Lupus familis
XP_538251
744
80557
P16
R
A
G
P
P
P
G
P
P
G
L
S
S
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHD9
1186
124492
S433
Q
V
L
E
K
I
E
S
E
Q
Y
K
K
E
M
Rat
Rattus norvegicus
Q8CGU4
1186
124419
S433
Q
V
L
E
K
P
E
S
E
Q
Y
K
K
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508850
681
74893
Chicken
Gallus gallus
XP_421880
1213
132309
G459
V
Q
E
E
S
P
E
G
G
R
F
K
K
E
I
Frog
Xenopus laevis
Q6NRL1
864
95088
W136
P
E
A
Q
F
A
M
W
V
D
A
V
I
F
V
Zebra Danio
Brachydanio rerio
XP_001921526
831
91170
E103
R
D
E
G
G
P
P
E
A
Q
F
A
L
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NGC3
995
108026
R267
V
I
D
D
T
R
A
R
K
L
A
S
D
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.8
60.5
N.A.
95.3
95.6
N.A.
28.6
42.4
38.5
38.6
N.A.
26.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98.3
61.1
N.A.
96.6
96.8
N.A.
37.6
55.7
50.6
49.5
N.A.
41.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
0
33.3
0
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
0
53.3
13.3
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
10
0
10
0
19
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
10
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
10
19
55
0
0
55
10
46
0
0
0
0
55
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
19
0
0
10
0
% F
% Gly:
0
0
10
10
10
0
10
10
10
10
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
46
0
0
0
10
0
0
55
55
0
10
% K
% Leu:
0
0
46
0
0
0
0
0
0
10
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
46
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
10
37
10
10
10
0
0
0
0
0
0
% P
% Gln:
46
10
0
10
0
0
0
0
0
55
0
0
0
0
0
% Q
% Arg:
19
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
46
0
0
0
19
10
0
10
% S
% Thr:
0
0
0
0
10
28
0
0
0
0
0
0
0
0
0
% T
% Val:
19
46
0
0
0
0
0
0
10
0
0
10
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _